BDBM327511 (S)-2-(1-((4-fluorophenyl)sulfonyl)-6-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-1,2,3,4-tetrahydroquinolin-2-yl)-1-(3-hydroxyazetidin-1-yl)ethanone::US9663469, 50

SMILES OC1CN(C1)C(=O)C[C@@H]1CCc2cc(ccc2N1S(=O)(=O)c1ccc(F)cc1)C(O)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=BLBDURVDDQPEOM-INIZCTEOSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 327511   

TargetNuclear receptor ROR-gamma [262-507](Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM327511((S)-2-(1-((4-fluorophenyl)sulfonyl)-6-(1,1,1,3,3,3...)
Affinity DataIC50:  19.6nMAssay Description:The binding of potential ligands to RORγ is measured by competition with [3H] 25-hydroxycholesterol using a scintillation proximity assay (SPA) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent