BDBM327832 2-((R)-2-methyl-4-((R)-phenyl(3-(trifluoromethyl)phenyl)methyl)piperazin-1-yl)acetic acid::US9663476, Compound 24

SMILES C[C@@H]1CN(CCN1CC(O)=O)[C@H](c1ccccc1)c1cccc(c1)C(F)(F)F

InChI Key InChIKey=QNCGXRCZIJEMGS-FOIQADDNSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 327832   

TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM327832(2-((R)-2-methyl-4-((R)-phenyl(3-(trifluoromethyl)p...)
Affinity DataIC50:  0.980nMAssay Description:This cell-based assay measures the ability of test compounds to inhibit the uptake of glycine by the glycine transporter type 1. Human placental chor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent