BDBM327833 (S)-2-((R)-4-(bis(4-chlorophenyl)methyl)-3-methylpiperazin-1-yl)propanoic acid::US9663476, Compound 79

SMILES C[C@H](N1CCN(C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)[C@H](C)C1)C(O)=O

InChI Key InChIKey=FTCZTBBFXDTQRT-CABCVRRESA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 327833   

TargetSodium- and chloride-dependent glycine transporter 1(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM327833((S)-2-((R)-4-(bis(4-chlorophenyl)methyl)-3-methylp...)
Affinity DataIC50:  2.14nMAssay Description:This cell-based assay measures the ability of test compounds to inhibit the uptake of glycine by the glycine transporter type 1. Human placental chor...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent