BDBM327922 5-(4-(4- fluorobenzyl)piperazine- 1-carbonyl)-(6-(4- cyanophenoxy)pyridin- 3-yl)picolinamide::US10377742, Compound 63::US9663496, Compound 63

SMILES Fc1ccc(CN2CCN(CC2)C(=O)c2ccc(nc2)C(=O)Nc2ccc(Oc3ccc(cc3)C#N)nc2)cc1

InChI Key InChIKey=SXCVHBDVDRBZIC-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 327922   

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Homo sapiens (Human))
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM327922(5-(4-(4- fluorobenzyl)piperazine- 1-carbonyl)-(6-(...)
Affinity DataEC50: <500nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Homo sapiens (Human))
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM327922(5-(4-(4- fluorobenzyl)piperazine- 1-carbonyl)-(6-(...)
Affinity DataEC50: <500nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent