BDBM328026 US10377742, Compound 164::US9663496, Compound 164::tert-butyl 3-(2-(1-(4- cyanobenzyl)piperidin-4- ylcarbamoyl)-5-(4-(4- fluorobenzyl)piperazine- 1-carbonyl)pyridin-3- yl)prop-2-ynylcarbamate

SMILES CC(C)(C)OC(=O)NCC#Cc1cc(cnc1C(=O)NC1CCN(Cc2ccc(cc2)C#N)CC1)C(=O)N1CCN(Cc2ccc(F)cc2)CC1

InChI Key InChIKey=MUQUTLCBPZXGBA-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 328026   

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Homo sapiens (Human))
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM328026(US10377742, Compound 164 | US9663496, Compound 164...)
Affinity DataEC50:  750nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Homo sapiens (Human))
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM328026(US10377742, Compound 164 | US9663496, Compound 164...)
Affinity DataEC50:  750nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent