BDBM32823 1-benzotriazolyl-(1,3-diphenyl-4-pyrazolyl)methanone::Benzotriazol-1-yl-(1,3-diphenyl-1H-pyrazol-4-yl)-methanone::MLS000556310::SMR000147627::benzotriazol-1-yl-(1,3-diphenylpyrazol-4-yl)methanone::cid_1409855

SMILES O=C(c1cn(nc1-c1ccccc1)-c1ccccc1)n1nnc2ccccc12

InChI Key InChIKey=CYQKPQNCLCVFKT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 32823   

TargetCoagulation factor XII(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32823(1-benzotriazolyl-(1,3-diphenyl-4-pyrazolyl)methano...)
Affinity DataIC50:  4.43E+3nMpH: 7.4 T: 2°CAssay Description:HTS was performed on a total of 33,068 compounds of the MLSCN library, 23,017 of which were not in the mixture HTS plates used previously. These comp...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCoagulation factor XII(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32823(1-benzotriazolyl-(1,3-diphenyl-4-pyrazolyl)methano...)
Affinity DataIC50:  4.43E+3nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCoagulation factor XI(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32823(1-benzotriazolyl-(1,3-diphenyl-4-pyrazolyl)methano...)
Affinity DataIC50: >5.00E+4nMpH: 7.4 T: 2°CAssay Description:Factor XIa (0.23 ug/mL) was incubated with Boc-Glu-Ala-Arg-AMC substrate (15 uM) in 10 uL of assay buffer for 2 hr at room temperature. Read fluoresc...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay