BDBM328247 N-(1-(4- cyanobenzyl)piperidin-4- yl)-6-(4-(2- (dimethylamino)-4- methoxyphenoxy) piperidine-1- carbonyl)nicotinamide::US10377742, Compound 385::US9663496, Compound 385

SMILES COc1ccc(OC2CCN(CC2)C(=O)c2ccc(cn2)C(=O)NC2CCN(Cc3ccc(cc3)C#N)CC2)c(c1)N(C)C

InChI Key InChIKey=USKHWBFFPMZFMQ-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 328247   

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Homo sapiens (Human))
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM328247(N-(1-(4- cyanobenzyl)piperidin-4- yl)-6-(4-(2- (di...)
Affinity DataEC50: >1.00E+4nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Homo sapiens (Human))
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM328247(N-(1-(4- cyanobenzyl)piperidin-4- yl)-6-(4-(2- (di...)
Affinity DataEC50: >1.00E+4nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent