BDBM328278 US10377742, Compound 416::US9663496, Compound 416::tert-butyl 3-(5-(1-(4- cyanobenzyl)piperidin-4- ylcarbamoyl)-2-(4-(4- methoxybenzoyl) piperidine-1- carbonyl)pyridin-3- yl)propylcarbamate

SMILES COc1ccc(cc1)C(=O)C1CCN(CC1)C(=O)c1ncc(cc1CCCNC(=O)OC(C)(C)C)C(=O)NC1CCN(Cc2ccc(cc2)C#N)CC1

InChI Key InChIKey=UUICOLGNKPZDCW-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 328278   

Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Homo sapiens (Human))
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM328278(US10377742, Compound 416 | US9663496, Compound 416...)
Affinity DataEC50:  3.00E+3nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target5'-AMP-activated protein kinase catalytic subunit alpha-2(Homo sapiens (Human))
Rigel Pharmaceuticals

US Patent
LigandPNGBDBM328278(US10377742, Compound 416 | US9663496, Compound 416...)
Affinity DataEC50:  3.00E+3nMAssay Description:Compounds were assayed for their ability to activate AMPK using an enzyme-linked immunosorbent assay. Reagents and procedures for measuring AMPK acti...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent