BindingDB logo
myBDB logout

BDBM328366 4-fluoro-1-((4-methoxy-3-(4-methylpiperazin-1-yl)phenyl)sulfonyl)-1H-indole::US9663498, Example 6

SMILES: COc1ccc(cc1N1CCN(C)CC1)S(=O)(=O)n1ccc2c(F)cccc12

InChI Key: InChIKey=MJIVXGXOYLXKCS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 328366   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM328366
PNG
(4-fluoro-1-((4-methoxy-3-(4-methylpiperazin-1-yl)p...)
Show SMILES COc1ccc(cc1N1CCN(C)CC1)S(=O)(=O)n1ccc2c(F)cccc12
Show InChI InChI=1S/C20H22FN3O3S/c1-22-10-12-23(13-11-22)19-14-15(6-7-20(19)27-2)28(25,26)24-9-8-16-17(21)4-3-5-18(16)24/h3-9,14H,10-13H2,1-2H3
Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 0.430n/an/an/an/an/an/a



SUNSHINE LAKE PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...


US Patent US9663498 (2017)

More data for this
Ligand-Target Pair