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BDBM328378 6-fluoro-1-((4-methoxy-3-(4-methylpiperazin-1-yl)phenyl)sulfonyl)-1H-indole::US9663498, Example 18

SMILES: COc1ccc(cc1N1CCN(C)CC1)S(=O)(=O)n1ccc2ccc(F)cc12

InChI Key: InChIKey=SCSWSUGKACTEML-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 328378   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM328378
PNG
(6-fluoro-1-((4-methoxy-3-(4-methylpiperazin-1-yl)p...)
Show SMILES COc1ccc(cc1N1CCN(C)CC1)S(=O)(=O)n1ccc2ccc(F)cc12
Show InChI InChI=1S/C20H22FN3O3S/c1-22-9-11-23(12-10-22)19-14-17(5-6-20(19)27-2)28(25,26)24-8-7-15-3-4-16(21)13-18(15)24/h3-8,13-14H,9-12H2,1-2H3
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KEGG

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PC cid
PC sid
UniChem
US Patent
n/an/a 0.670n/an/an/an/an/an/a



SUNSHINE LAKE PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...


US Patent US9663498 (2017)

More data for this
Ligand-Target Pair