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BDBM328382 7-fluoro-1-((4-methoxy-3-(piperazin-1-yl)phenyl)sulfonyl)-1H-indole::US9663498, Example 22

SMILES: COc1ccc(cc1N1CCNCC1)S(=O)(=O)n1ccc2cccc(F)c12

InChI Key: InChIKey=FHDILDPZVASRQL-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 328382   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM328382
PNG
(7-fluoro-1-((4-methoxy-3-(piperazin-1-yl)phenyl)su...)
Show SMILES COc1ccc(cc1N1CCNCC1)S(=O)(=O)n1ccc2cccc(F)c12
Show InChI InChI=1S/C19H20FN3O3S/c1-26-18-6-5-15(13-17(18)22-11-8-21-9-12-22)27(24,25)23-10-7-14-3-2-4-16(20)19(14)23/h2-7,10,13,21H,8-9,11-12H2,1H3
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KEGG

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PC cid
PC sid
UniChem
US Patent
n/an/a 0.570n/an/an/an/an/an/a



SUNSHINE LAKE PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...


US Patent US9663498 (2017)

More data for this
Ligand-Target Pair