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BDBM328396 6-chloro-1-((3-(4-cyclopropylpiperazin-1-yl)-4-methoxyphenyl) sulfonyl)-3-(difluoromethyl)-1H-indole::US9663498, Example 39

SMILES: COc1ccc(cc1N1CCN(CC1)C1CC1)S(=O)(=O)n1cc(C(F)F)c2ccc(Cl)cc12

InChI Key: InChIKey=LYMZAKGJYMLURF-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 328396   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM328396
PNG
(6-chloro-1-((3-(4-cyclopropylpiperazin-1-yl)-4-met...)
Show SMILES COc1ccc(cc1N1CCN(CC1)C1CC1)S(=O)(=O)n1cc(C(F)F)c2ccc(Cl)cc12
Show InChI InChI=1S/C23H24ClF2N3O3S/c1-32-22-7-5-17(13-21(22)28-10-8-27(9-11-28)16-3-4-16)33(30,31)29-14-19(23(25)26)18-6-2-15(24)12-20(18)29/h2,5-7,12-14,16,23H,3-4,8-11H2,1H3
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PC cid
PC sid
UniChem
US Patent
n/an/a 0.0920n/an/an/an/an/an/a



SUNSHINE LAKE PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...


US Patent US9663498 (2017)

More data for this
Ligand-Target Pair