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BDBM328399 3-(difluoromethyl)-1-((4-methoxy-3-(piperazin-1-yl)phenyl) sulfonyl)-6-(trifluoromethyl)-1H-indole::US9663498, Example 44

SMILES: COc1ccc(cc1N1CCNCC1)S(=O)(=O)n1cc(C(F)F)c2ccc(cc12)C(F)(F)F

InChI Key: InChIKey=FNBUCBPCPSKCOA-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 328399   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM328399
PNG
(3-(difluoromethyl)-1-((4-methoxy-3-(piperazin-1-yl...)
Show SMILES COc1ccc(cc1N1CCNCC1)S(=O)(=O)n1cc(C(F)F)c2ccc(cc12)C(F)(F)F
Show InChI InChI=1S/C21H20F5N3O3S/c1-32-19-5-3-14(11-18(19)28-8-6-27-7-9-28)33(30,31)29-12-16(20(22)23)15-4-2-13(10-17(15)29)21(24,25)26/h2-5,10-12,20,27H,6-9H2,1H3
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PC cid
PC sid
UniChem
US Patent
n/an/a 0.400n/an/an/an/an/an/a



SUNSHINE LAKE PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...


US Patent US9663498 (2017)

More data for this
Ligand-Target Pair