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BDBM328412 6-chloro-3-ethyl-1-((4-methoxy-3-(piperazin-1-yl)phenyl)sulfonyl)-1H-indole::US9663498, Example 71

SMILES: CCc1cn(c2cc(Cl)ccc12)S(=O)(=O)c1ccc(OC)c(c1)N1CCNCC1

InChI Key: InChIKey=LCHNKDOUXKWFEN-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 328412   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Serotonin (5-HT) receptor


(Homo sapiens (Human))
BDBM328412
PNG
(6-chloro-3-ethyl-1-((4-methoxy-3-(piperazin-1-yl)p...)
Show SMILES CCc1cn(c2cc(Cl)ccc12)S(=O)(=O)c1ccc(OC)c(c1)N1CCNCC1
Show InChI InChI=1S/C21H24ClN3O3S/c1-3-15-14-25(19-12-16(22)4-6-18(15)19)29(26,27)17-5-7-21(28-2)20(13-17)24-10-8-23-9-11-24/h4-7,12-14,23H,3,8-11H2,1-2H3
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PC cid
PC sid
UniChem
US Patent
n/an/a 0.450n/an/an/an/an/an/a



SUNSHINE LAKE PHARMA CO., LTD.

US Patent


Assay Description
The binding affinity of the compound of this invention to human 5-HT6 receptor expressed in CHO cell was evaluated by radioligand binding assay as fo...


US Patent US9663498 (2017)

More data for this
Ligand-Target Pair