BDBM328479 (S)-1,1,1-trifluoro-2-methylpropan-2- yl (2-(acetamidomethyl)-4-((4- fluoro-3- (trifluoromethyl)phenyl)sulfonyl)- 3,4-dihydro-2H-benzo[b][1,4]oxazin- 6-yl)carbamate::US9663502, 10D
SMILES CC(=O)NC[C@H]1CN(c2cc(NC(=O)OC(C)(C)C(F)(F)F)ccc2O1)S(=O)(=O)c1ccc(F)c(c1)C(F)(F)F
InChI Key InChIKey=LTFYNANRXQQAQD-AWEZNQCLSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 328479
Affinity DataIC50: 3.35nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair