BDBM328716 (S)-1,1,1-trifluoro-2- methylpropan-2-yl (4-((4- fluorophenyl)sulfonyl)-2-((2- (tetrahydro-2H-pyran-4- yl)acetamido)methyl)-3,4- dihydro-2H- benzo[b][1,4]oxazin-6- yl)carbamate::US9663502, 34U

SMILES CC(C)(OC(=O)Nc1ccc2O[C@H](CNC(=O)CC3CCOCC3)CN(c2c1)S(=O)(=O)c1ccc(F)cc1)C(F)(F)F

InChI Key InChIKey=YOUXOVHZCKYMAX-HXUWFJFHSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 328716   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Lycera

US Patent
LigandPNGBDBM328716((S)-1,1,1-trifluoro-2- methylpropan-2-yl (4-((4- f...)
Affinity DataIC50:  3.92nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., a biochemical TR-FRET assay....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent