BDBM329084 4-(5-chloro-6-(2,4-dichloro-6- methylphenoxy)-3-pyridinyl)-3- (difluoromethoxy)-N- (methylsulfonyl)benzamide::4-(5-chloro-6-(2,4-dichloro-6-methylphenoxy)-3-pyridinyl)-3-(difluoromethoxy)-N-(methylsulfonyl)benzamide::US9663508, Example 585

SMILES Cc1cc(Cl)cc(Cl)c1Oc1ncc(cc1Cl)-c1ccc(cc1OC(F)F)C(=O)NS(C)(=O)=O

InChI Key InChIKey=UZMSDLFEGBEWHD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 329084   

TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM329084(4-(5-chloro-6-(2,4-dichloro-6- methylphenoxy)-3-py...)
Affinity DataIC50:  289nMAssay Description:293 cells stably transfected with human Nav 1.5 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology syste...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM329084(4-(5-chloro-6-(2,4-dichloro-6- methylphenoxy)-3-py...)
Affinity DataIC50:  47.2nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent