BDBM329110 4-(6-(4-tert-butyl-2- chlorophenoxy)-5-chloro-3- pyridinyl)-2-fluoro-5-methyl- N-(methylsulfonyl)benzamide::4-(6-(4-tert-butyl-2-chlorophenoxy)-5-chloro-3-pyridinyl)-2-fluoro-5-methyl-N-(methylsulfonyl)benzamide::US9663508, Example 611

SMILES Cc1cc(C(=O)NS(C)(=O)=O)c(F)cc1-c1cnc(Oc2ccc(cc2Cl)C(C)(C)C)c(Cl)c1

InChI Key InChIKey=TVWCZKNYUKPXSL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 329110   

TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM329110(4-(6-(4-tert-butyl-2- chlorophenoxy)-5-chloro-3- ...)
Affinity DataIC50: >3.00E+3nMAssay Description:293 cells stably transfected with human Nav 1.5 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology syste...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Amgen

US Patent
LigandPNGBDBM329110(4-(6-(4-tert-butyl-2- chlorophenoxy)-5-chloro-3- ...)
Affinity DataIC50:  76.1nMAssay Description:HEK 293 cells stably transfected with human Nav1.7 were recorded in whole cell voltage clamp mode with the PatchXpress automated electrophysiology sy...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent