BDBM329394 5-(3,5-difluorophenyl)- 2-methyl-4-(((1S,2S)-2- (5-methylpyridin-2- yl)cyclopropyl)methoxy) pyrimidine::US9663513, 7

SMILES Cc1ccc(nc1)[C@H]1C[C@@H]1COc1nc(C)ncc1-c1cc(F)cc(F)c1

InChI Key InChIKey=WWHXMERMFWEUHE-QAPCUYQASA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 329394   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM329394(5-(3,5-difluorophenyl)- 2-methyl-4-(((1S,2S)-2- (5...)
Affinity DataKi:  0.460nMAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, Sunny...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent