BDBM329394 5-(3,5-difluorophenyl)- 2-methyl-4-(((1S,2S)-2- (5-methylpyridin-2- yl)cyclopropyl)methoxy) pyrimidine::US9663513, 7
SMILES Cc1ccc(nc1)[C@H]1C[C@@H]1COc1nc(C)ncc1-c1cc(F)cc(F)c1
InChI Key InChIKey=WWHXMERMFWEUHE-QAPCUYQASA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 329394
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 0.460nMAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, Sunny...More data for this Ligand-Target Pair