BDBM329462 5-(2-ethoxypyridin-4-yl)- 4-(((1S,2S)-2-(5- methoxypyridin-2- yl)cyclopropyl)methoxy)- 2-methylpyrimidine::US9663513, 75

SMILES CCOc1cc(ccn1)-c1cnc(C)nc1OC[C@H]1C[C@@H]1c1ccc(OC)cn1

InChI Key InChIKey=RYLJLKGZQCMLEZ-AEFFLSMTSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 329462   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM329462(5-(2-ethoxypyridin-4-yl)- 4-(((1S,2S)-2-(5- methox...)
Affinity DataKi:  0.140nMAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, Sunny...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent