BDBM329472 5-(6-ethylpyridin-3-yl)-4- (((1S,2S)-2-(5- methoxypyridin-2- yl)cyclopropyl)methoxy)- 2-methylpyrimidine::US9663513, 85

SMILES CCc1ccc(cn1)-c1cnc(C)nc1OC[C@H]1C[C@@H]1c1ccc(OC)cn1

InChI Key InChIKey=JNJUTFFGOXSBRN-APWZRJJASA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 329472   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM329472(5-(6-ethylpyridin-3-yl)-4- (((1S,2S)-2-(5- methoxy...)
Affinity DataKi:  0.860nMAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, Sunny...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent