BDBM329544 2-(5-(2-methyl-4- (((1S,2S)-2-(quinolin-2- yl)cyclopropyl)methoxy) pyrimidin-5-yl)pyridin-2- yl)propan-2-ol::US9663513, 157

SMILES Cc1ncc(-c2ccc(nc2)C(C)(C)O)c(OC[C@H]2C[C@@H]2c2ccc3ccccc3n2)n1

InChI Key InChIKey=DFLYFNVDNXIMHM-UXHICEINSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 329544   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM329544(2-(5-(2-methyl-4- (((1S,2S)-2-(quinolin-2- yl)cycl...)
Affinity DataKi:  0.0200nMAssay Description:The fluorescence polarization assay for cyclic nucleotide phosphodiesterases was performed using an IMAP® FP kit supplied by Molecular Devices, Sunny...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent