BDBM329703 2-(1-(1-(2-chloro-6- (trifluoromethyl)benzoyl)-4-fluoro-1H- indazol-3- yl)piperidin-4- yl)acetic acid::US9663522, 1J::US9663522, 1K

SMILES OC(=O)CC1CCN(CC1)c1nn(C(=O)c2c(Cl)cccc2C(F)(F)F)c2cccc(F)c12

InChI Key InChIKey=SIBDLELXBCCIIF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 329703   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM329703(2-(1-(1-(2-chloro-6- (trifluoromethyl)benzoyl)-4-f...)
Affinity DataIC50:  164nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM329703(2-(1-(1-(2-chloro-6- (trifluoromethyl)benzoyl)-4-f...)
Affinity DataIC50:  7.76E+3nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent