BDBM329720 (1R,5S)-9-(1-(2-chloro-6- (trifluoromethyl)benzyl)- 4-fluoro-1H-indazol-3-yl)-9- azabicyclo[3.3.1] nonane-3-carboxylic acid::US9663522, 5B

SMILES OC(=O)C1C[C@@H]2CCC[C@H](C1)N2c1nn(Cc2c(Cl)cccc2C(F)(F)F)c2cccc(F)c12

InChI Key InChIKey=MBIBZLHCULWLDA-GOOCMWNKSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 329720   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM329720((1R,5S)-9-(1-(2-chloro-6- (trifluoromethyl)benzyl)...)
Affinity DataIC50:  6.59E+3nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent