BDBM329721 1-(1-(2-chloro-6- (trifluoromethyl)benzoyl)-4-fluoro- 1H-indazol-3-yl)-2-ethylpiperidine-4- carboxylic acid::US9663522, 5C

SMILES CCC1CC(CCN1c1nn(C(=O)c2c(Cl)cccc2C(F)(F)F)c2cccc(F)c12)C(O)=O

InChI Key InChIKey=MOBQHWPJHITMOP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 329721   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM329721(1-(1-(2-chloro-6- (trifluoromethyl)benzoyl)-4-fluo...)
Affinity DataIC50:  1.42E+3nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent