BDBM329907 (s.e.)-((1R,2R,3S,4R)-2,3-dihydroxy-4-(2-(4-methylnaphthalen-1-yl)pyrazolo[1,5-::US10202389, Compound I-115::US9663525, Compound I-115::US9796725, Compound I-115

SMILES Cc1ccc(-c2cc3nccc(N[C@@H]4C[C@H](COS(N)(=O)=O)[C@@H](O)[C@H]4O)n3n2)c2ccccc12

InChI Key InChIKey=MLTHMAMGZPVLHX-CAIJCGSQSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 329907   

TargetUbiquitin-conjugating enzyme E2 E1(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM329907((s.e.)-((1R,2R,3S,4R)-2,3-dihydroxy-4-(2-(4-methyl...)
Affinity DataIC50: <10nMAssay Description:The UAE enzymatic reaction totals 50 μL and contains 50 mmol HEPES (pH 7.5), 0.05% BSA, 2.5 mM MgCl2, 0.1 uM ATP, 8 nM GST-Ubc-2, 35 nM flag-ubi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSUMO-activating enzyme subunit 2(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM329907((s.e.)-((1R,2R,3S,4R)-2,3-dihydroxy-4-(2-(4-methyl...)
Affinity DataIC50: <10nMAssay Description:he UAE enzymatic reaction totals 50 μL and contains 50 mmol HEPES (pH 7.5), 0.05% BSA, 2.5 mM MgCl2, 0.1 uM ATP, 8 nM GST-Ubc-2, 35 nM flag-ubiq...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin-like modifier-activating enzyme 1(Homo sapiens (Human))
Millennium Pharmaceuticals

US Patent
LigandPNGBDBM329907((s.e.)-((1R,2R,3S,4R)-2,3-dihydroxy-4-(2-(4-methyl...)
Affinity DataIC50: <10nMAssay Description:The UAE enzymatic reaction totals 50 μL and contains 50 mmol HEPES (pH 7.5), 0.05% BSA, 2.5 mM MgCl2, 0.1 uM ATP, 8 nM GST-Ubc-2, 35 nM flag-ubi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent