BDBM329916 (s.e.)-{(1R,2R,3S,4R)-4-[(3,6-dichloro-2-{3-::US10202389, Compound I-124::US9663525, Compound I-124::US9796725, Compound I-124
SMILES NS(=O)(=O)OC[C@H]1C[C@@H](Nc2c(Cl)cnc3c(Cl)c(nn23)-c2cccc(SC(F)(F)F)c2)[C@H](O)[C@@H]1O
InChI Key InChIKey=MZWFHZDGVLGVPB-NRXFTUCASA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 329916
Affinity DataIC50: 550nMAssay Description:The UAE enzymatic reaction totals 50 μL and contains 50 mmol HEPES (pH 7.5), 0.05% BSA, 2.5 mM MgCl2, 0.1 uM ATP, 8 nM GST-Ubc-2, 35 nM flag-ubi...More data for this Ligand-Target Pair
Affinity DataIC50: 550nMAssay Description:he UAE enzymatic reaction totals 50 μL and contains 50 mmol HEPES (pH 7.5), 0.05% BSA, 2.5 mM MgCl2, 0.1 uM ATP, 8 nM GST-Ubc-2, 35 nM flag-ubiq...More data for this Ligand-Target Pair
TargetUbiquitin-like modifier-activating enzyme 1(Homo sapiens (Human))
Millennium Pharmaceuticals
US Patent
Millennium Pharmaceuticals
US Patent
Affinity DataIC50: 550nMAssay Description:The UAE enzymatic reaction totals 50 μL and contains 50 mmol HEPES (pH 7.5), 0.05% BSA, 2.5 mM MgCl2, 0.1 uM ATP, 8 nM GST-Ubc-2, 35 nM flag-ubi...More data for this Ligand-Target Pair