BDBM32999 8-Ethyl-4-phenyl-1-thia-4-aza-spiro[4.5]decan-3-one::8-ethyl-4-phenyl-1-thia-4-azaspiro[4.5]decan-3-one::MLS001012148::SMR000425321::cid_703600

SMILES CCC1CCC2(CC1)SCC(=O)N2c1ccccc1

InChI Key InChIKey=XDEUTSZKPUPFOT-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 32999   

TargetCoagulation factor XI(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32999(8-Ethyl-4-phenyl-1-thia-4-aza-spiro[4.5]decan-3-on...)
Affinity DataIC50: >5.00E+4nMpH: 7.4 T: 2°CAssay Description:Factor XIa (0.23 ug/mL) was incubated with Boc-Glu-Ala-Arg-AMC substrate (15 uM) in 10 uL of assay buffer for 2 hr at room temperature. Read fluoresc...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetHeat shock factor protein 1(Mus musculus)
Broad Institute

Curated by PubChem BioAssay
LigandPNGBDBM32999(8-Ethyl-4-phenyl-1-thia-4-aza-spiro[4.5]decan-3-on...)
Affinity DataEC50: >2.60E+5nMAssay Description:Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Confirmation testing of small molecules identifie...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetKallikrein-5(Homo sapiens (Human))
Pcmd

Curated by PubChem BioAssay
LigandPNGBDBM32999(8-Ethyl-4-phenyl-1-thia-4-aza-spiro[4.5]decan-3-on...)
Affinity DataIC50:  5.00E+4nMAssay Description:Molecular Library Screening Center Network (MLSCN) Penn Center for Molecular Discovery (PCMD) Assay Provider: Scott L. Diamond, University of Pennsy...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay