BDBM330043 (2S,5R,13aS)-N—((S)-1-(2,4-difluorophenyl)ethyl)-8-hydroxy-7,9-dioxo-2,3,4,5,7,9,13,13a-octahydro-2,5-methanopyrido[1′,2′:4,5]pyrazino[2,1-b][1,3]oxazepine-10-carboxamide::US11548901, Compound 13::US9663528, 13::US9732092, Compound 13

SMILES C[C@H](NC(=O)c1cn2C[C@@H]3O[C@H]4CC[C@H](C4)N3C(=O)c2c(O)c1=O)c1ccc(F)cc1F

InChI Key InChIKey=HZQGBUQIMZZLDE-IMODNSLOSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 330043   

TargetSolute carrier family 22 member 2(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM330043((2S,5R,13aS)-N—((S)-1-(2,4-difluorophenyl)eth...)
Affinity DataIC50:  610nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSolute carrier family 22 member 2(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM330043((2S,5R,13aS)-N—((S)-1-(2,4-difluorophenyl)eth...)
Affinity DataIC50:  610nMAssay Description:The dose dependent inhibition of OCT2 mediated uptake of a model substrate 14C-Tetraethylammonium (TEA) by test compounds was studied in wild-type an...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSolute carrier family 22 member 2(Homo sapiens (Human))
Gilead Sciences

US Patent
LigandPNGBDBM330043((2S,5R,13aS)-N—((S)-1-(2,4-difluorophenyl)eth...)
Affinity DataIC50:  610nMAssay Description:Test compounds were serially diluted in DMSO and then spiked (2 μL) into in 0.4 mL KHB buffer containing wild-type or OCT2-transfected cells and...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent