BDBM330075 N-(5H-chromeno [3,4-c]pyridin- 8-yl)-2-(2,4- dichlorophenyl) acetamide::US9663529, Example I-14

SMILES Clc1ccc(CC(=O)Nc2ccc-3c(OCc4cnccc-34)c2)c(Cl)c1

InChI Key InChIKey=WUMAJJYZZADKLC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 330075   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM330075(N-(5H-chromeno [3,4-c]pyridin- 8-yl)-2-(2,4- dichl...)
Affinity DataIC50:  54.4nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent