BDBM330111 N-(5H-chromeno[3,4- c]pyridin- 8-yl)benzamide::US9663529, Example I-50

SMILES O=C(Nc1ccc-2c(OCc3cnccc-23)c1)c1ccccc1

InChI Key InChIKey=DUVUUGLVISMAJM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 330111   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM330111(N-(5H-chromeno[3,4- c]pyridin- 8-yl)benzamide | US...)
Affinity DataIC50:  4.81E+3nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent