BDBM330114 3-chloro-N-(5H- chromeno[3,4- c]pyridin-8- yl)benzamide::US9663529, Example I-53

SMILES Clc1cccc(c1)C(=O)Nc1ccc-2c(OCc3cnccc-23)c1

InChI Key InChIKey=BMZJYEWABRAFIN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 330114   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM330114(3-chloro-N-(5H- chromeno[3,4- c]pyridin-8- yl)benz...)
Affinity DataIC50:  4.50E+3nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent