BDBM330116 N-(5H-chromeno[3,4- c]pyridin-8-yl)-4- methoxybenzamide::US9663529, Example I-55

SMILES COc1ccc(cc1)C(=O)Nc1ccc-2c(OCc3cnccc-23)c1

InChI Key InChIKey=RBFZEPNKWCKAHI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 330116   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM330116(N-(5H-chromeno[3,4- c]pyridin-8-yl)-4- methoxybenz...)
Affinity DataIC50:  3.25E+3nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent