BDBM330123 N-(5H-chromeno[3,4- c]pyridin-8-yl)-2- phenylacetamide::US9663529, Example I-62
SMILES O=C(Cc1ccccc1)Nc1ccc-2c(OCc3cnccc-23)c1
InChI Key InChIKey=YBOFPWRUNWZIOF-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 330123
Affinity DataIC50: 43.6nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Affinity DataIC50: 140nMAssay Description:Inhibition of ROCK1 (unknown origin) using FITC-AHA-AKRRRLSSLRA-OH as substrate by caliper assayMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMAssay Description:Inhibition of ROCK2 (unknown origin) using FITC-AHA-AKRRRLSSLRA-OH as substrate by caliper assayMore data for this Ligand-Target Pair