BDBM330155 2-(3-Fluorophenyl)-N-(9H-pyrido[3,4-b]indol-7-yl)acetamide::US9663529, Example IV-3

SMILES Fc1cccc(CC(=O)Nc2ccc3c(c2)[nH]c2cnccc32)c1

InChI Key InChIKey=OFPHWKCSWMZJGJ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 330155   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM330155(2-(3-Fluorophenyl)-N-(9H-pyrido[3,4-b]indol-7-yl)a...)
Affinity DataIC50:  21nMAssay Description:The effectiveness of compounds of the present invention as ROCK inhibitors can be determined in a 30 μL assay containing 20 mM HEPES, pH 7.5, 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent