BDBM330183 N-[4-[[(1 S,4S)-5-Oxa-2-azabicyclo[2.2.1]heptan-4-yl]methyl]phenyl]-6-(2,2,2-trifluoroethoxy)pyridine-3-carboxamide::US9663530, Example 27

SMILES FC(F)(F)COc1ccc(cn1)C(=O)Nc1ccc(C[C@]23CN[C@H](CO2)C3)cc1

InChI Key InChIKey=WHQWIDMUYVZOHH-LPHOPBHVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 330183   

TargetTrace amine-associated receptor 1(Rattus norvegicus (Rat))
Hoffmann-La Roche

US Patent
LigandPNGBDBM330183(N-[4-[[(1 S,4S)-5-Oxa-2-azabicyclo[2.2.1]heptan-4-...)
Affinity DataIC50:  13nMAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM330183(N-[4-[[(1 S,4S)-5-Oxa-2-azabicyclo[2.2.1]heptan-4-...)
Affinity DataIC50:  55.2nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent