BDBM330217 N-[4-[(1 S,4R)-5-Oxa-2-azabicyclo[2.2.1]heptan-4-yl]phenyl]-5-(trifluoromethyl)pyridin-2-amine::US9663530, Example 61

SMILES FC(F)(F)c1ccc(Nc2ccc(cc2)[C@]23CN[C@H](CO2)C3)nc1

InChI Key InChIKey=CGPJLLQBODFQPP-HOCLYGCPSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 330217   

TargetTrace amine-associated receptor 1(Rattus norvegicus (Rat))
Hoffmann-La Roche

US Patent
LigandPNGBDBM330217(N-[4-[(1 S,4R)-5-Oxa-2-azabicyclo[2.2.1]heptan-4-y...)
Affinity DataIC50:  29.3nMAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM330217(N-[4-[(1 S,4R)-5-Oxa-2-azabicyclo[2.2.1]heptan-4-y...)
Affinity DataIC50:  14.6nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent