BDBM330222 (RS)-1-(4-Chlorophenyl)-3-[4-(5-oxa-2-azabicyclo[2.2.2]octan-4-yl)phenyl]urea::US9663530, Example 66

SMILES Clc1ccc(NC(=O)Nc2ccc(cc2)C23CCC(CO2)NC3)cc1

InChI Key InChIKey=VTUKFFWLZDTJSP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 330222   

TargetTrace amine-associated receptor 1(Rattus norvegicus (Rat))
Hoffmann-La Roche

US Patent
LigandPNGBDBM330222((RS)-1-(4-Chlorophenyl)-3-[4-(5-oxa-2-azabicyclo[2...)
Affinity DataIC50:  46.5nMAssay Description:HEK-293 cells stably expressing mouse TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTrace amine-associated receptor 1(Mus musculus (Mouse))
Hoffmann-La Roche

US Patent
LigandPNGBDBM330222((RS)-1-(4-Chlorophenyl)-3-[4-(5-oxa-2-azabicyclo[2...)
Affinity DataIC50:  5nMAssay Description:HEK-293 cells stably expressing rat TAAR1 were maintained at 37° C. and 5% CO2 in DMEM high glucose medium, containing fetal calf serum (10%, heat in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent