BDBM330397 US9725436, Entry 16

SMILES Fc1cc(Cn2ccnc2)cc(\C=C\c2ccc(cc2)N2CCN(CC2)S(=O)(=O)C[N+]#[C-])c1

InChI Key InChIKey=TZXSYFKSVMSTCF-NSCUHMNNSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 330397   

TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Bos taurus (Bovine))
Cortendo AB (PUBL)

US Patent
LigandPNGBDBM330397(US9725436, Entry 16)
Affinity DataIC50:  86nMAssay Description:Cyp17 assay protocol: AD293 cells that stably over-express recombinant CYP-17 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Bos taurus (Bovine))
Cortendo AB (PUBL)

US Patent
LigandPNGBDBM330397(US9725436, Entry 16)
Affinity DataIC50:  1.00E+4nMAssay Description:Cyp21 assay protocol: AD293 cells that stably over-express recombinant CYP-21 were seeded in 96 well plates coated with poly D-lysine (10,000 cell pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCholesterol side-chain cleavage enzyme, mitochondrial(Bos taurus (Bovine))
Cortendo AB (PUBL)

US Patent
LigandPNGBDBM330397(US9725436, Entry 16)
Affinity DataIC50:  73nMAssay Description:Cyp11 assay protocol: AD293 cells that stably over-express recombinant CYP-11 were seeded in 96 well plates coated with poly D-lysine (15,000 cell pe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent