BDBM331547 N-((S)-2-((3aS,6S,6aS)-6-chloro-3-oxotetrahydro-2H-furo[3,2-b]pyrrol-4(5H)-yl)-1-cyclohexyl-2-oxoethyl)-5-(pyridin-3-yl)furan-2-carboxamide::US9725459, 10

SMILES Cl[C@H]1CN([C@H]2[C@@H]1OCC2=O)C(=O)[C@@H](NC(=O)c1ccc(o1)-c1cccnc1)C1CCCCC1

InChI Key InChIKey=VPDWNQHHCKCYRB-FBEWHJACSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 331547   

TargetCathepsin K(Homo sapiens (Human))
Grunenthal

US Patent
LigandPNGBDBM331547(N-((S)-2-((3aS,6S,6aS)-6-chloro-3-oxotetrahydro-2H...)
Affinity DataKi:  54nMAssay Description:Recombinant human cathepsins (CatS, CatK, CatL) were purchased from a Enzo Life Sciences. All assays were carried out in 96-well format using a buffe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Grunenthal

US Patent
LigandPNGBDBM331547(N-((S)-2-((3aS,6S,6aS)-6-chloro-3-oxotetrahydro-2H...)
Affinity DataKi:  612nMAssay Description:Recombinant human cathepsins (CatS, CatK, CatL) were purchased from a Enzo Life Sciences. All assays were carried out in 96-well format using a buffe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent