BDBM331558 N-((S)-2-((3aS,6S,6aS)-6-chloro-3-oxotetrahydro-2H-furo[3,2-b]pyrrol-4(5H)-yl)-1-cyclohexyl-2-oxoethyl)-4-methyl-2-(pyrazin-2-yl)thiazole-5-carboxamide::US9725459, 22

SMILES Cc1nc(sc1C(=O)N[C@@H](C1CCCCC1)C(=O)N1C[C@H](Cl)[C@H]2OCC(=O)[C@@H]12)-c1cnccn1

InChI Key InChIKey=GXJMTVXMVCKZOI-WQANXHIZSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 331558   

TargetCathepsin K(Homo sapiens (Human))
Grunenthal

US Patent
LigandPNGBDBM331558(N-((S)-2-((3aS,6S,6aS)-6-chloro-3-oxotetrahydro-2H...)
Affinity DataKi:  37nMAssay Description:Recombinant human cathepsins (CatS, CatK, CatL) were purchased from a Enzo Life Sciences. All assays were carried out in 96-well format using a buffe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent