BDBM331574 N-((S)-2-((3aS,6S,6aS)-6-chloro-3- oxotetrahydro-2H-furo[3,2-b]pyrrol-4(5H)-yl)- 1-cyclohexyl-2-oxoethyl)-5-(5-cyanopyridin- 3-yl)thiophene-2-carboxamide::US9725459, 39

SMILES Cl[C@H]1CN([C@H]2[C@@H]1OCC2=O)C(=O)[C@@H](NC(=O)c1ccc(s1)-c1cncc(c1)C#N)C1CCCCC1

InChI Key InChIKey=HWJVUROICHNXPI-AIZKBTNYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 331574   

TargetCathepsin K(Homo sapiens (Human))
Grunenthal

US Patent
LigandPNGBDBM331574(N-((S)-2-((3aS,6S,6aS)-6-chloro-3- oxotetrahydro-2...)
Affinity DataKi:  19nMAssay Description:Recombinant human cathepsins (CatS, CatK, CatL) were purchased from a Enzo Life Sciences. All assays were carried out in 96-well format using a buffe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Grunenthal

US Patent
LigandPNGBDBM331574(N-((S)-2-((3aS,6S,6aS)-6-chloro-3- oxotetrahydro-2...)
Affinity DataKi:  225nMAssay Description:Recombinant human cathepsins (CatS, CatK, CatL) were purchased from a Enzo Life Sciences. All assays were carried out in 96-well format using a buffe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent