BDBM331589 N-((S)-2-((3aS,6S,6aS)-6-chloro-3- oxotetrahydro-2H-furo[3,2-b]pyrrol-4(5H)-yl)- 1-cyclohexyl-2-oxoethyl)-4-fluoro-5- (pyridazin-3-yl)thiophene-2-carboxamide::US9725459, 54

SMILES Fc1cc(sc1-c1cccnn1)C(=O)N[C@@H](C1CCCCC1)C(=O)N1C[C@H](Cl)[C@H]2OCC(=O)[C@@H]12

InChI Key InChIKey=KIGJQHZQBSCHKN-YGHPHNMRSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 331589   

TargetCathepsin K(Homo sapiens (Human))
Grunenthal

US Patent
LigandPNGBDBM331589(N-((S)-2-((3aS,6S,6aS)-6-chloro-3- oxotetrahydro-2...)
Affinity DataKi:  21nMAssay Description:Recombinant human cathepsins (CatS, CatK, CatL) were purchased from a Enzo Life Sciences. All assays were carried out in 96-well format using a buffe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCathepsin S(Homo sapiens (Human))
Grunenthal

US Patent
LigandPNGBDBM331589(N-((S)-2-((3aS,6S,6aS)-6-chloro-3- oxotetrahydro-2...)
Affinity DataKi:  528nMAssay Description:Recombinant human cathepsins (CatS, CatK, CatL) were purchased from a Enzo Life Sciences. All assays were carried out in 96-well format using a buffe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent