BDBM331723 US9725465, Example 144

SMILES COc1cc2nc(cnc2cc1OC1COC1)-c1ccc(CC(=O)Nc2cc(on2)C2(CC2)C(F)(F)F)c(F)c1

InChI Key InChIKey=GYVNJYOZTFPARX-UHFFFAOYSA-N

Data  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 331723   

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Ambit Biosciences

US Patent
LigandPNGBDBM331723(US9725465, Example 144)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
Ambit Biosciences

US Patent
LigandPNGBDBM331723(US9725465, Example 144)
Affinity DataKd: <5nMAssay Description:Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent