BDBM331977 (R)- or (S)-2- methyl-6-(1-(1- (4-(trifluoro- methyl)phenyl) ethyl)-1H- imidazol-4-yl) pyrimidin-4 (3H)-one::US10195201, Example 16::US10195201, Example 17
SMILES CC(c1ccc(cc1)C(F)(F)F)n1cnc(c1)-c1cc(=O)[nH]c(C)n1
InChI Key
Data 3 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 331977
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 76nMAssay Description:The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluorescence polarization...More data for this Ligand-Target Pair
Affinity DataKi: 106nMAssay Description:The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluorescence polarization...More data for this Ligand-Target Pair
Affinity DataKi: 340nMAssay Description:The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluorescence polarization...More data for this Ligand-Target Pair