BDBM332128 US10189854, Compound 84::[1-[5-(2-Fluorophenyl)-pyrimidin-2-yl]-spiro[1,2-dihydro-indole-3,1'-cyclopropane]-6-yl]-piperidin-1-yl-methanone

SMILES Fc1ccccc1-c1cnc(nc1)N1CC2(CC2)c2ccc(cc12)C(=O)N1CCCCC1

InChI Key InChIKey=WGQWPYRYFKJOGF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 332128   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Homo sapiens (Human))
Gruenenthal

US Patent
LigandPNGBDBM332128(US10189854, Compound 84 | [1-[5-(2-Fluorophenyl)-p...)
Affinity DataIC50: <100nMAssay Description:The inhibiting effect of the compounds on the enzyme activity of human PDE4B1 was measured by the quantification of 5′-adenosine monophosphate ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent