BDBM332425 3-fluoro-4-(1- (tetrahydro- furan-2- carbonyl)-1H- indazol-3-yl) benzoic acid::US10196354, Example 1U::US9745265, 1U
SMILES OC(=O)c1ccc(-c2nn(C(=O)C3CCCO3)c3ccccc23)c(F)c1
InChI Key InChIKey=RQLYGRRZWKTFLU-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 332425
Affinity DataIC50: >1.00E+4nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I...More data for this Ligand-Target Pair