BDBM332431 4-(1-(2- chloro-6- cyclopropyl- benzoyl)-4- fluoro-1H- indazol-3- yl)-3-fluoro- benzoic acid::US10196354, Example 1AA::US9745265, 1AA
SMILES OC(=O)c1ccc(-c2nn(C(=O)c3c(Cl)cccc3C3CC3)c3cccc(F)c23)c(F)c1
InChI Key InChIKey=ITAJZCHZGRGIEJ-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 332431
Affinity DataIC50: 2nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
Affinity DataIC50: 2nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I...More data for this Ligand-Target Pair