BDBM332436 4-(1-(2-chloro-6- (trifluoromethyl) benzoyl)-6- ((2S,6R)-2,6- dimethyl- morpholine-4- carbonyl)-1H- indazol-3-yl)-3- fluorobenzoic acid::US10196354, Example 2B::US9745265, 2B
SMILES C[C@H]1CN(C[C@@H](C)O1)C(=O)c1ccc2c(nn(C(=O)c3c(Cl)cccc3C(F)(F)F)c2c1)-c1ccc(cc1F)C(O)=O
InChI Key InChIKey=FYCDYBZKAVRDMF-GASCZTMLSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 332436
Affinity DataIC50: 15nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I...More data for this Ligand-Target Pair