BDBM332467 4-(1-(2-chloro- 6-(trifluoromethyl) benzoyl)-6- (hydroxy(oxazol- 2-yl)methyl)-1H- pyrazolo[4,3- b]pyridine-3-yl)-3-fluorobenzoic acid::US10196354, Example 8C::US9745265, 8C
SMILES OC(c1ncco1)c1cnc2c(nn(C(=O)c3c(Cl)cccc3C(F)(F)F)c2c1)-c1ccc(cc1F)C(O)=O
InChI Key InChIKey=WDPHOVASCHHXHY-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 332467
Affinity DataIC50: 218nMAssay Description:To identify novel antagonists of RORgammaT, an assay was developed which employs the interaction of RORgammaT with its co-activator peptide SRC1_2. T...More data for this Ligand-Target Pair
Affinity DataIC50: 218nMAssay Description:The compounds of the invention inhibit RORgammaT activity. Activation of RORgammaT activity can be measured using, e.g., biochemical TR-FRET assay. I...More data for this Ligand-Target Pair